Article: The relationships among physiologic variables, quality of life, and fatigue in patients with multiple myeloma.(Article)(Report)

Fatigue is a symptom with several possible etiologic factors related to disease and treatment, including low hemoglobin (hgb), nutritional deficiencies, cytokines, cachexia, tumor burden, anxiety, depression, sleep disturbance, physical activity, and unmanaged symptoms (Ahlberg, Ekman, Gaston-Johansson, & Mock, 2003; Morrow, Shelke, Roscoe, Hickok, & Mustian, 2005; Olson et al., 2008). Fatigue in cancer has been described as being unlike fatigue associated with normal physical or mental exertion, with distinct physical, sensory, affective, and cognitive components (Barnes & Bruera, 2002; Gutstein, 2001; Olson & Morse, 2005). A consequence of the disease and treatment, ...

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