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Article: Ascorbic acid preferentially enhances type I and III collagen gene transcription in human skin fibroblasts.(Vitamin C)(Report)
- Article from:
- Life Extension
- Article date:
- May 1, 2009
CopyrightCOPYRIGHT 2009 LE Publications, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Ascorbic acid is a potent stimulator for type I and III collagen expression in human skin fibroblasts; stimulation of type I and III collagen synthesis and their mRNA levels by ascorbic acid has been reported previously. Nuclear run-on experiments demonstrated that ascorbic acid enhanced the transcription of type I and III collagen genes 4- and 3.4-fold ...
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