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Article: Researchers from Stanford University report details of new studies and findings in the area of prostate cancer.(Report)
- Article from:
- Cancer Weekly
- Article date:
- May 26, 2009
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"Calcitriol (1,25-dihydroxyvitamin D-3) inhibits the growth of a variety of cancer cells including human prostate cancer. Mullerian-inhibiting substance (MIS) also exhibits antiproliferative and proapoptotic actions on multiple cancer cells including human prostate cancer," scientists in the United States report (see also Prostate Cancer).
"In this study, we investigated whether calcitriol regulated MIS expression in prostate cancer, an action that might contribute to its antiproliferative activity. We identified a 15-bp sequence, GGGTGAgcaGGGACA, in the MIS promoter that was highly similar to direct repeat 3-type vitamin D response elements (VDREs). The human ...
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