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Article: New bioconjugate chemistry study findings have been published by P.D. Pollheimer and colleagues.
- Article from:
- Chemicals & Chemistry
- Article date:
- May 29, 2009
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According to a study from Linz, Austria, "We describe microarrays of receptors on gold/glass substrates for the selective capturing of viral particles at high density. Microscale gold squares were surface-modified with alkanethiol derivatives which enabled the immobilization of the HiS(6)-tagged virus-binding domain from the very-low density lipoprotein (VLDL) receptor."
"The free glass areas surrounding the gold squares were passivated with a dense film of poly(ethylene glycol) (PEG). As assessed by atomic force microscopy, human rhinovirus particles were captured onto the VLDL-receptor patches with a high surface coverage but were effectively repelled by the ...