Article: CryoLife gets FDA clearance for new immune response claim for its pulmonary human heart valve.

CryoLife, Inc., Atlanta, GA, announced that the US Food and Drug Administration (FDA) has cleared a new claim for the CryoValve SG pulmonary human heart valve. The new labeling claim relates to reducing a component of the immune response of the CryoValve SG.

The company says the new claim was validated from data provided from three clinical studies and a comprehensive review of the scientific literature on allograft heart valves showed that implantation of the CryoValve SG reduces the risk of inducing HLA class I and class II alloantibodies, based on Panel Reactive Antibody (PRA) measured at up to one year, compared to the standard-processed pulmonary human heart ...

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