|
|
Article: New colon cancer study results reported from National Cancer Institute.
- Article from:
- Cancer Weekly
- Article date:
- June 2, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
"The Wnt/APC/beta-catenin signaling pathway, which includes frizzled-related protein (FRZB), plays a critical role in the development of colorectal cancer, and recent evidence suggests that the functional polymorphism, FRZB Arg324Gly, may be associated with risk for this disease. To determine if this finding could be replicated, we investigated the association between two FRZB polymorphisms (Arg324Gly and Arg200Trp) and the risk of colorectal adenoma and cancer in nested case-control studies," researchers in the United States report (see also Colon Cancer).
"Participants consisted of 1,709 adenoma cases, 620 cancer cases, and 1,849 controls within the Prostate, ...