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Article: New findings in angiogenesis described from Harvard University, Medical Department.
- Article from:
- Obesity & Diabetes Week
- Article date:
- June 1, 2009
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According to recent research from the United States, "Many of the current in vivo methods to evaluate angiogenesis are poorly quantifiable. Recently, the Matrigel plug assay has become the method of choice in many studies involving in vivo testing for angiogenesis."
"When known angiogenic factors are mixed with Matrigel and injected subcutaneously into mice, endothelial cells migrate into the gel plug. These endothelial cells form vessel-like structures, a process that mimics the formation of capillary networks. Here, we present a modification of the traditional Matrigel assay with improved method to quantify the amount of endothelial cells that incorporate into ...
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