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Article: Studies from University of Pittsburgh in the area of tissue engineering described.(Report)
- Article from:
- Blood Weekly
- Article date:
- June 11, 2009
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"The porcine small intestine submucosa, an extracellular matrix-derived bioscaffold (ECM-SIS), has been successfully used to enhance the healing of ligaments and tendons. Since the collagen fibers of ECM-SIS have an orientation of +/- 30 degrees, its application in improving the healing of the parallel-fibered ligament and tendon may not be optimal," scientists writing in the journal Tissue Engineering Part a report (see also Tissue Engineering).
"Therefore, the objective was to improve the collagen fiber alignment of ECM-SIS in vitro with fibroblast seeding and cyclic stretch. The hypothesis was that with the synergistic effects of cell seeding and mechanical ...