Article: Research on addiction medicine reported by scientists at University of Sao Paulo.(Report)

New research, 'Amphetamine- and nicotine-induced cross-sensitization in adolescent rats persists until adulthood,' is the subject of a report. According to recent research from Sao Paulo, Brazil, "Nicotine and psychostimulants are often abused in combination and drug abuse often begins during adolescence and can have long-term consequences. Behavioral sensitization has been suggested as an animal model of neuroplasticity implicated in the development of drug addiction."

"We evaluated whether the pretreatment with nicotine (0.4 mg/kg; s.c.) or amphetamine (5.0 mg/kg; i.p.) in adolescent rats [from postnatal day (P) 28 to P34] could induce cross-sensitization to ...

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