Article: Alitretinoin for hand eczema.(PIPELINE PREVIEWS)(Brief article)

Basilea Pharmaceutica Ltd. recently announced that it has commenced a phase 3 trial of alitretinoin for the treatment of severe chronic hand eczema. This trial, entitled the HANDEL trial (HAND Eczema research of alitretinoin), is a multicentered, placebo-controlled, randomized clinical study to evaluate the safety and efficacy of alitretinoin in patients with severe chronic hand eczema in the United States. Alitretinoin has already been approved in Europe for severe chronic hand eczema that has been refractory to standard topical steroids.

Six hundred patients in approximately 90 sites in the United States will be randomly assigned to receive either oral ...

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