Article: Other News To Note.

Addex Pharmaceuticals Inc., of Geneva, achieved a second preclinical milestone in its partnership with Merck & Co., of Whitehouse Station, N.J., and will receive $500,000. The firm was able to show the desired non-dopaminergic activity profile after oral administration of metabotropic glutamate receptor 4-positive allosteric modulator in an animal model of Parkinson's disease. The collaboration is focused on developing allosteric modulators that activate mGluR4 for Parkinson's disease and other undisclosed indications. Addex received $250,000 after achieving the first preclinical milestone during the first quarter of last year. (See BioWorld Today, Jan. 4, 2008.)

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