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Article: Toxic chemicals affect steroid hormones differently in humans and invertebrates.
- Article from:
- Chemicals & Chemistry Business
- Article date:
- July 17, 2009
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In a study with important consequences for studies on the effects of chemicals on steroid responses in humans, a team of French and American scientists, including Michael E. Baker, PhD, professor in UC San Diego's Department of Medicine, Division of Nephrology-Hypertension, have found that - contrary to earlier assumptions - enzymes used for the synthesis of steroids in insects, snails, octopuses and corals are unrelated to those used in humans.
The research, led by a team at the Universite de Lyon, ENS Lyon, provides insight into the evolution of steroid hormone signaling and the relationship of steroid synthesis to enzymes that detoxify harmful chemicals in the ...