Article: Data on biological chemistry described by researchers at Johns Hopkins University, Department of Biological Chemistry.

Fresh data on biological chemistry are presented in the report 'O-linked beta-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins.' "O-GlcNAc-transferase (OGT) substrate specificity is regulated by transiently interacting proteins. To further examine the regulation of OGT, we have identified 27 putative OGT-interacting proteins through a yeast two-hybrid screen," researchers in the United States report (see also Biological Chemistry).

"Two of these proteins, Trak1 (OIP106) and O-GlcNAcase, have been shown previously to interact with and regulate OGT. We demonstrate here that MYPT1 and ...

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