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Article: Scientists at Leiden University describe research in cancer therapy.
- Article from:
- Cancer Weekly
- Article date:
- July 28, 2009
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New investigation results, 'Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array,' are detailed in a study published in British Journal of Cancer. In this recently published article, scientists in Leiden, Netherlands conducted a study "To identify new polymorphisms (single nucleotide polymorphisms, SNPs) in DNA repair pathways that are associated with efficacy and toxicity in patients receiving oxaliplatin and capecitabine for advanced colorectal cancer (ACC). We studied progression-free survival (PFS) in 91 ACC patients, of whom germ-line DNA was isolated and genotyped using an Asper Biotech array."
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