|
|
Article: Research data from University of Iowa update understanding of bacteriology.
- Article from:
- Science Letter
- Article date:
- August 4, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
According to recent research published in the Journal of Bacteriology, "The opportunistic pathogen Pseudomonas aeruginosa utilizes a type III secretion system (T3SS) to evade phagocytosis and damage eukaryotic cells. Transcription of the T3SS regulon is controlled by ExsA, a member of the AraC/XylS family of transcriptional regulators."
"These family members generally consist of an similar to 100-amino acid carboxy-terminal domain (CTD) with two helix-turn-helix DNA binding motifs and an similar to 200-amino acid amino-terminal domain (NTD) with known functions including oligomerization and ligand binding. In the present study, we show that the CTD of ExsA binds ...