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Article: Data on life sciences reported by N. Kunert and co-researchers.
- Article from:
- Proteomics Weekly
- Article date:
- March 23, 2009
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Investigators publish new data in the report 'dMec: a novel Mi-2 chromatin remodelling complex involved in transcriptional repression.' According to a study from Marburg, Germany, "The ATP-dependent chromatin remodeller Mi-2 functions as a transcriptional repressor and contributes to the suppression of cell fates during development in several model organisms. Mi-2 is the ATPase subunit of the conserved Nucleosome Remodeling and Deacetylation (NuRD) complex, and transcriptional repression by Mi-2 is thought to be dependent on its associated histone deacetylase."
"Here, we have purified a novel dMi-2 complex from Drosophila that is distinct from dNuRD. dMec (dMEP-1 ...
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