Article: Twin study examines associations between depression and coronary artery disease.

Major depression and coronary artery disease are only modestly related throughout an individual's lifetime, but studying how the two interact over time and in twin pairs paints a more complex picture of the associations between the conditions, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals. For example, the association between coronary artery disease onset and major depression risk is much stronger over time than vice versa.

"While an association between major depression and coronary artery disease has long been noted and recently confirmed, the direction and cause of this association remain ...

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