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Article: Findings in vascular endothelial growth factor reported from Dublin City University.
- Article from:
- Angiogenesis Weekly
- Article date:
- August 21, 2009
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"Notch, VEGF, and components of the Hedgehog (Hh) signaling pathway have been implicated in vascular morphogenesis. The role of Notch in mediating hedgehog control of adult vascular smooth muscle cell (SMC) growth and survival remains unexplored," investigators in Dublin, Ireland report (see also Vascular Endothelial Growth Factor).
"In cultured SMCs, activation of Hh signaling with recombinant rShh (3.5 mu g/mL) or plasmid encoded Shh increased Ptc1 expression, enhanced SMC growth and survival and promoted Hairy-related transcription factor (Hrt) expression while concomitantly increasing VEGF-A levels. These effects were significantly reversed after Hh ...
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Article: Scientists at Dublin City University target ...
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... ... Stokes and colleagues, Dublin City University. The researchers concluded ... information, contact J. Stokes, Dublin City University, Materials Processing Research ... Materials Engineering, Dublin City University. This article was prepared ...
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