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Article: Research from A.S. Valles and co-researchers provides new data on pharmaceutical research.
- Article from:
- Drug Week
- Article date:
- August 21, 2009
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According to a study from Bahia Blanca, Argentina, "Studies of the alpha 7-type neuronal nicotinic acetylcholine receptor (AChR), one of the receptor forms involved in many physiologically relevant processes in the central nervous system, have been hampered by the inability of this homomeric protein to assemble in most heterologous expression systems. In a recent study, it was shown that the chaperone Ric-3 is necessary for the maturation and functional expression of alpha 7-type AChRs([1])."
"The current work aims at obtaining and characterizing a cell line with high functional expression of the human alpha 7 AChR. Ric-3 cDNA was incorporated into SHE-P1-h alpha ...