Article: Research on atherosclerosis detailed by scientists at Nara Medical University, Second Department of Internal Medicine.(Report)

A new study, 'Nocturnal hypoxic stress activates invasive ability of monocytes in patients with obstructive sleep apnoea syndrome,' is now available. "Obstructive sleep apnoea syndrome (OSAS) is known to be a risk factor for cardiovascular events. However, the precise mechanism has not been fully elucidated," investigators in Nara, Japan report (see also Atherosclerosis).

"OSAS-induced hypoxic stress may promote the production of inflammatory cytokines and chemokines by monocytes, which has a crucial role in the development of atherosclerosis. In addition, adhesion to the vascular endothelium and transendothelial migration of monocytes are considered to induce ...

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