|
|
Article: Study argues ACE inhibitors should not be used in some heart patients.(Clinical report)
- Article from:
- Drug Formulary Review
- Article date:
- January 1, 2005
CopyrightCOPYRIGHT 2005 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
Study argues ACE inhibitors should not be used in some heart patients
Trial results should change practice immediately, physician says
A new study argues that many heart patients receiving modern conventional therapy do not benefit from angiotensin-converting-enzyme (ACE) inhibitors if the patients have stable coronary heart disease and preserved left ventricular function.
The double-blind, placebo-controlled trial studied 8,290 patients, who were randomly assigned to receive either trandolapril at a dose of 4 mg per day or matching placebo. The patients, who were followed for a median of 4.8 years, had normal or near-normal left ventricular ...