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Article: Cardiac-Resynchronization Therapy in Advanced Chronic Heart Failure.

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Clinical Cardiology Alert
Article date:
July 1, 2004
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Cardiac-Resynchronization Therapy in Advanced Chronic Heart Failure

Abstract & Commentary

Synopsis: In selected patients, cardiac resynchronization therapy with a pacemaker or pacemaker-defibrillator improves their clinical course and the addition of a defibrillator with cardiac resynchronization therapy alone further reduces mortality.

Source: Bristow MR, et al. N Engl J Med. 2004;350:2140-2150.

Previous studies on cardiac resynchronization therapy (CRT) have used an improvement in heart failure symptoms or a decrease in hospitalization as their primary end points and have not had adequate statistical power to detect changes in ...

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