Article: Clinical Briefs: Melatonin for Jet Lag.

Clinical Briefs: Melatonin for Jet Lag

With Comments from John LaPuma, MD, FACP

Source: Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev 2002;(2): CD001520.

Jet lag commonly affects air travelers who cross several time zones. It results from the bodys internal rhythms being out of step with the day-night cycle at the destination. Melatonin is a pineal hormone that plays a central part in regulating bodily rhythms and has been used as a drug to re-align them with the outside world.

To assess the effectiveness of oral melatonin taken in different dosage regimens for alleviating ...

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