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Article: Studies from University of Cagliari further understanding of carcinoma.
- Article from:
- Cancer Weekly
- Article date:
- September 1, 2009
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"Basal cell carcinoma (BCC) is a very common malignant skin tumor that rarely metastatizes, but is often locally aggressive. Several factors, like large size (more than 3 cm), exposure to ultraviolet rays, histological variants, level of infiltration and perineural or perivascular invasion, are associated with a more aggressive clinical course," scientists in Cagliari, Italy report (see also Carcinoma).
"These morphological features seem to be more determinant in mideface localized BCC, which frequently show a significantly higher recurrence rate. An immunohistochemical profile, characterized by reactivity of tumor cells for p53, Ki67 and alpha-SMA has been ...