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Article: Recent findings from G. Desguetz and co-authors highlight research in colon cancer.
- Article from:
- Cancer Weekly
- Article date:
- September 1, 2009
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"Microsatellite instability (MSI) status in predicting the efficacy of adjuvant chemotherapy in colorectal cancer remains controversial. Studies were identified through PubMed, Embase and ASCO proceedings with a combination of keywords (colorectal cancer, chemotherapy and MSI)," scientists in Bobigny, France report (see also Colon Cancer).
"A MA was performed for treated and non-treated MSI population on seven studies. Statistical calculations were performed on 7 studies representing 3690 patients; mean age: 65.5 years; 810 stage II and 2444 stage III (75%). MSI-high (MSI-H) was found in 454 patients (14% of the global population), and microsatellite stable (MSS) ...