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Article: Tubal Ligation Shown to Reduce Incidence of Ovarian Cancer for BRCA1 Carriers.
- Article from:
- Internal Medicine Alert
- Article date:
- July 15, 2001
CopyrightCOPYRIGHT 2001 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Tubal Ligation Shown to Reduce Incidence of Ovarian Cancer for BRCA1 Carriers
ABSTRACT & COMMENTARY
Synopsis: Ovarian cancer occurs frequently in women who carry the BRCA1 and BRCA2 gene mutations. In this multinational, retrospective, case-control study, a prior tubal ligation was shown to provide significant protection against subsequent ovarian cancer development. Thus, tubal ligation is a feasible option to reduce risk of ovarian cancer in women with BRCA1 mutations who have completed childbearing.
Source: Narod SA, et al. Lancet. 2001;357:1467-1470.
The lifetime risk for ovarian cancer in women who carry mutations in the BRCA1 or ...