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Article: Postmenopausal Hormone Use and Secondary Prevention of Coronary Events in the Nurses' Health Study.
- Article from:
- Internal Medicine Alert
- Article date:
- October 29, 2001
CopyrightCOPYRIGHT 2001 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Postmenopausal Hormone Use and Secondary Prevention of Coronary Events in the Nurses Health Study
Abstract & Commentary
Synopsis: The risk of recurrent major coronary events was mildly increased by short-term (
Source: Grodstein F, et al. Ann Intern Med. 2001;135:1-8.
The Heart and Estrogen/progestin Replacement Study (HERS) hypothesized that postmenopausal hormone use in women with established cardiovascular disease would reduce recurrence of cardiovascular events. In this study, 2763 women with active heart disease were randomized to either placebo or Prempro.sup.[R] and followed for 5 years. In the first year, the rate of recurrence was 52% higher ...