Article: Postmenopausal Hormone Use and Secondary Prevention of Coronary Events in the Nurses' Health Study.

Postmenopausal Hormone Use and Secondary Prevention of Coronary Events in the Nurses Health Study

Abstract & Commentary

Synopsis: The risk of recurrent major coronary events was mildly increased by short-term (

Source: Grodstein F, et al. Ann Intern Med. 2001;135:1-8.

The Heart and Estrogen/progestin Replacement Study (HERS) hypothesized that postmenopausal hormone use in women with established cardiovascular disease would reduce recurrence of cardiovascular events. In this study, 2763 women with active heart disease were randomized to either placebo or Prempro.sup.[R] and followed for 5 years. In the first year, the rate of recurrence was 52% higher ...

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