Article: Natural Killer Cells and Cancer: Immune Surveillance Revisited.(Clinical report)

Natural Killer Cells and Cancer: Immune Surveillance Revisited

ABSTRACT & COMMENTARY

Synopsis: The presence of immune surveillance against cancer has been difficult to establish in humans. In this longitudinal analysis of a relatively large cohort of individuals for whom a baseline level of lymphocyte (NK cell)-mediated natural cytotoxicity, it was found after 11 years that a lower baseline level of activity was associated with a greater risk for cancer. This report may provide the strongest evidence for the presence of immune surveillance in humans.

Source: Imai K, et al. Lancet 2000;356:1795-1799.

The concept of immune surveillance, ...

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