Article: Breast Cancer Surveillance for High-Risk Women.

Breast Cancer Surveillance for High-Risk Women

ABSTRACT & COMMENTARY

Synopsis: The effectiveness of breast cancer surveillance in high-risk women, including BRCA1/2 mutation carriers, was evaluated in a retrospective study of 1198 women 449 moderate risk, 15-30% estimated lifetime breast cancer risk; 621 high risk, 30-50% estimated lifetime breast cancer risk; and 128 BRCA1/2 mutation carriers, and 60-85% estimated lifetime breast cancer risk. Screening consisted of instructions for monthly breast self-examination, clinical breast exam every 6-12 months, yearly mammography, optional use of breast MRI in more recently screened patients, and median ...

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