Article: A Prospective Study of New Infections with Herpes Simplex Virus Type 1 and Type 2.(Clinical report)

A Prospective Study of New Infections with Herpes Simplex Virus Type 1 and Type 2

abstract & commentary

Synopsis: Nearly half of all newly acquired HSV-2 infections are asymptomatic. Asymptomatic infections are more common in men than in women.

Source: Langenberg AG, et al. N Engl J Med 1999;341: 1432-1438.

This project was initially developed to study the effectiveness of a vaccine for the prevention of herpes simplex virus (HSV) infection. The trial vaccine was found to be ineffective. However, Langenberg and colleagues determined that the participants were appropriate for a prospective study of infection with HSV types 1 and 2. The ...

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