Article: Long-Term Treatment with Inhaled Budesonide in Persons with Mild COPD who Continue Smoking.

Long-Term Treatment with Inhaled Budesonide in Persons with Mild COPD who Continue Smoking

Abstract & Commentary

Synopsis: This paper outlines the effect of the inhaled steroid budesonide on patients with mild COPD who continue to smoke. Pauwels and colleagues report that there was a significant early (6 months) difference between patients who received the steroid vs. placebo, which then remained throughout the entire trial (3 years). This difference was more marked for those patients who had less than a 36-pack-year smoking history.

Source: Pauwels RA, et al. N Engl J Med 1999;340: 1948-1953.

Chronic obstructive pulmonary disease ...

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