Article: Reducing Surgical Wound Infections with Supplemental Oxygen.

Reducing Surgical Wound Infections with Supplemental Oxygen

Abstract & Commentary

Synopsis: In a randomized trial, supplemental 80% oxygen was associated with a 54% reduction in surgical site infections among patients undergoing colorectal surgery.

Source: Greif R, et al. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med 2000;342:161-167.

Greif and colleagues randomized 500 patients undergoing elective colorectal resection to receive either 30% or 80% oxygen during surgery and for two hours after extubation. The presence or absence of wound infection during the first 15 days post- ...

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