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Article: Protection from Cancer by Anti-inflammatory Drugs.(Clinical report)
- Article from:
- Clinical Oncology Alert
- Article date:
- September 1, 2000
CopyrightCOPYRIGHT 2000 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Protection from Cancer by Anti-inflammatory Drugs
ABSTRACT & COMMENTARY
Synopsis: A history of nonsteroidal anti-inflammatory drug use was examined in a large series of cancer patients and controls from the United Kingdom. Long-term use was associated with a decreased risk of colorectal, esophageal, and gastric cancer, but possibly an increased risk of pancreatic and prostatic cancers. No effect was seen on the development of breast or bladder cancer. Perhaps these findings are related to the known increased expression of the COX-2 gene in many of these tumors.
Source: Langman MJ, et al. BMJ 2000;320:1642-1646.
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