Article: Prospects for Rotavirus Vaccine.(Clinical report)

Prospects for Rotavirus Vaccine

ABSTRACT & COMMENTARY

Synopsis: Two recent studies of human-rhesus reassortant rotavirus vaccines have been found to be safe in children and efficacious in preventing severe rotavirus diarrheal illness and dehydration.

Sources: Santosham M, et al. Efficacy and safety of high-dose rhesus-human reassortant rotavirus vaccine in Native American populations. J Pediatr 1997;131:632-638; Perez-Schael I, et al. Efficacy of the rhesus rotavirus-based quadrivalent vaccine in infants and young children in Venezuela. N Engl J Med 1997;337:1181-1187.

A rhesus rotavirus tetravalent (serotypes g1-4) vaccine (RRV-TV), a ...

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