Article: Citalopram: New SSRI for Treatment of Depression.

Pharmacology Update

Citalopram: New SSRI for Treatment of Depression

By William T. Elliott, MD, and James Chan, PharmD, PhD

Anew selective serotonin reuptake inhibitor (SSRI), citalopram, was approved by the FDA in July for the treatment of depression. The drug is to be marketed under the trade name Celexa by Forest Laboratories and Parke-Davis. It is the fifth SSRI to be approved for use in this country, joining fluoxetine, paroxetine, sertraline, and fluvoxamine. Its action appears to be limited to the potentiation of serotonergic activity in the central nervous system, with minimal effect on norepinephrine and dopamine transmitter ...

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