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Article: Study findings on biological chemistry are outlined in reports from McMaster University.
- Article from:
- Chemicals & Chemistry
- Article date:
- September 11, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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"1,4-Dihydropyridines (DHPs) constitute a major class of ligands for L-type Ca2+ channels (LTCC). The DHPs have a boat-like, six-membered ring with an NH group at the stern, an aromatic moiety at the bow, and substituents at the port and starboard sides," researchers in Hamilton, Canada report.
"Various DHPs exhibit antagonistic or agonistic activities, which were previously explained as stabilization or destabilization, respectively, of the closed activation gate by the portside substituents. Here we report a novel structural model in which agonist and antagonist activities are determined by different parts of the DHP molecule and have different mechanisms. In ...
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Article: MCMASTER UNIVERSITY: McMaster to change direction ...
M2 Presswire;
September 28, 1999 ;
651 words
...M2 PRESSWIRE-28 September 1999-MCMASTER UNIVERSITY: McMaster University to change direction of undergraduate education ... COMMUNICATIONS LTD RDATE:270999 Hamilton -- McMaster University and Royal Bank Financial Group have joined ...
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