Article: P53, Angiopoietin-Like Protein 2 Both Implicated Studies: Links Among Obesity, Inflammation, Insulin Resistance.

Byline: Anette Breindl, Science Editor

Exactly what constitutes an optimal weight -- and the consequences of not being at one -- remains a subject of debate, and studies have come to differing conclusions about the relationship between weight, health and life expectancy. But obesity is linked to several health problems that are collectively known as metabolic syndrome -- a group of symptoms that predispose to coronary artery disease, Type II diabetes and stroke.

The two most important risk factors in metabolic syndrome are obesity -- especially central obesity, or extra weight around the middle -- and insulin resistance. Recent studies have pointed to a ...

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