Article: NSAIDs may increase GI bleeding risk in HD patients.

HEMODIALYSIS (HD) patients who make use of nonsteroidal antiinflammatory drugs (NSAIDs) are at increased risk for GI bleeding, a study shows.

From a population of 650 HD patients, Slobodan M. Jankovic, MD, PhD, and collaborators at the University of Kragujevac in Kragujevac, Serbia, selected 33 HD patients who experienced at least one episode of GI bleeding during the past three years and 45 age- and sex-matched controls who did not experience GI bleeding. After adjusting for numerous potential confounders, NSAID use was associated with a nearly sixfold increased risk of GI bleeding, investigators reported in the Journal of Nephrology (2009; 22:502-507). Use of ...

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