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Article: Characterization of V3 Loop-Pseudomonas exotoxin Chimeras - Candidate Vaccines for Human Immunodeficiency Virus-1.
- Article from:
- Vaccine Weekly
- Article date:
- May 25, 1998
CopyrightCOPYRIGHT 1998 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Fitzgerald, D.J.; Fryling, C.M.; Mckee, M.L.; Vennari, J.C.; Wrin, T.; Cromwell, M.E.M.; Daugherty, A.L.; Mrsny, R.J. "Characterization of V3 Loop-Pseudomonas exotoxin Chimeras - Candidate Vaccines for Human Immunodeficiency Virus-1." Journal of Biological Chemistry, April 17, 1998;273(16):9951-9958.
According to the authors' abstract of an article published in Journal of Biological Chemistry, "To develop a candidate vaccine for human immunodeficiency virus type 1 (HIV-1), chimeric proteins were constructed by inserting sequences derived from the V3 loop of gp120 into a nontoxic form of Pseudomonas exotoxin (PE). Inserts of 14 or 26 amino acids, constrained by a ...