Article: New data from INSERM illuminate research in gliomatosis.

"In gliomatosis cerebri (GC), defined as a diffuse neoplastic glial cell infiltration of the brain, upfront chemotherapy is often proposed as an alternative to radiotherapy. GC invades both white matter and gray matter in varying proportions, as reflected by the gray matter index (GMI), i.e., the estimated percentage of gray matter involvement," investigators in Paris, France report (see also Gliomatosis).

"The GMI was estimated in 71 patients with GC (42 men and 29 women; median age, 47 years) treated with upfront chemotherapy (7 PCV, 64 temozolomide). Median GMI was 30%. were separated into 2 groups according to this median GMI. Compared to the 33 patients with ...

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