Article: Research from J. Prosecka and co-authors yields new data on permease.

"The charged quaternary ammonium compounds - methyl, ethyl and benzyl viologens - generate reactive oxygen species in photosynthetic cells. Three independent methyl viologen-resistant spontaneous mutants of Synechocystis sp," investigators in Trebon, Czech Republic report (see also Permease).

"PCC 6803 were identified, in which the conserved R115 residue of the Slr1174 protein was replaced with G115, L115 and C115. The Slr1174 protein of the DUF990 family is related to the permease subunit of an ABC-2-type transporter and its R115 mutation was found to be solely responsible for the observed methyl viologen resistance. Bioinformatic analysis showed that in various ...

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