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Article: Reports outline vaccinia virus research from F.J. Chichon and colleagues.
- Article from:
- Vaccine Weekly
- Article date:
- September 23, 2009
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According to recent research from Madrid, Spain, "Information. VACV (vaccinia virus) is one of the most complex viruses, with a size exceeding 300 nm and more than 100 structural proteins."
"Its assembly involves sequential interactions and important rearrangements of its structural components. We have used electron tomography of sections of VACV-infected cells to follow, in three dimensions, the remodelling of the membrane components of the virus during envelope maturation. The tomograms obtained suggest that a number of independent 'crescents' interact with each other to enclose the volume of an incomplete ellipsoid in the viral factory area, attaining the ...