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Article: How to improve vaccines to trigger T cell as well as antibody response.
- Article from:
- NewsRx Health
- Article date:
- September 27, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Killed or disabled viruses have proven safe and effective for vaccinating billions worldwide against smallpox, polio, measles, influenza and many other diseases.
But killed or severely "attenuated" vaccines, which are safer than "live" vaccines, have been largely unsuccessful for many non-viral diseases, including illnesses like tuberculosis and malaria.
A new study by researchers from the University of California, Berkeley, and Berkeley-based Aduro BioTech provides clues why killed and severely attenuated vaccines don't always work. It also suggests ways to engineer an attenuated vaccine to make it as potent as a live vaccine but as safe as a killed ...