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Article: Findings from G.S. Nikolic and co-authors provide new insights into physical chemistry.
- Article from:
- Chemicals & Chemistry
- Article date:
- October 2, 2009
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"A selective, precise and new high-performance liquid chromatographic method for the analysis of loperamid hydrochloride in pharmaceutical formulations was developed and validated. The mobile phase consisting buffer (sodium-octansulphonate, triethylamine and ammonium hydroxide) in water: acetonitriie (45: 55, v/v) (pH 3.2)," scientists in Serbia report.
"The absorbance was monitored with a DAD detector at 226 nm. The flow rate was 1.5 cm(3) min(-1). The linearity (r = 0.9947) and the recovery (98.58-100.42%) were found to be satisfactory. The detection and quantitation limits were found to be 0.95 and 3.12 mu g cm(-3). The results demonstrated that the procedure ...