Article: New science research reported from C. Stumpf and co-authors.

According to a study from the United States, "A chromatographer's toolkit traditionally consists of the liquid chromatography system (LC), column, and UV detector, all controlled by the chromatography data system (CDS) software. Single quadrupole mass spectrometry made its way into the chromatographer's toolkit early on as a convenient tool for detecting analytes that lack UV-responsive chromophores."

"However, sample matrix interference often necessitates the need for more sensitive and selective tandem quadrupole mass spectrometers. Unfortunately, more MS stages have required more sophisticated operator skills and specialized mass spectrometer acquisition ...

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