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Article: Studies from C.C. Hsieh and co-researchers in the area of metals published.
- Article from:
- Journal of Technology
- Article date:
- September 29, 2009
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According to recent research published in the journal Organometallics, "The reaction of Ni(ClO4)(2) with 4 equiv of pyrazole (pzH) in MeCN leads to [Ni(pzH)(2)(HN=C(Me)pz)(2)](ClO4)(2) via the intermediate [Ni(MeCN)(2)(pzH)(4)](ClO4)(2), which is the first pyrazole-nitrile coupling reaction activated by a Ni(II) complex. The reaction is also successfully conducted with other nitriles RCN bearing an electron-donating group (R = Et, Bz) and is counteranion-specific."
"The reaction proceeds more quickly with NO3- as counteranion than with ClO4-, and BF4- is found to be unsatisfactory for the coupling reaction. As for the X-ray crystal structures, ...