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Article: Reports on clinical pharmacology findings from Jilin University provide new insights.(Clinical report)
- Article from:
- Drug Week
- Article date:
- October 9, 2009
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"Many traditional Chinese medicines have been used as immunomodulators that act as either immunosuppressants or immunostimulators. Recently, our lab successfully isolated a monomer telocinobufagin (TCB) from the chloroform extract of Chan Su (Venenum Bufonis)," investigators in Changchun, People's Republic of China report (see also Clinical Pharmacology).
"In the present paper, we evaluated the immunomodulatory effects of this compound in vitro. We found that TCB significantly stimulates splenocyte proliferation when administered alone or in combination with polyclonal T-cell mitogens concanavalin A (Con A) and lipopolysaccharide. Telocinobufagin markedly ...