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Article: Researchers from University of Heidelberg report on findings in angiogenesis.
- Article from:
- Angiogenesis Weekly
- Article date:
- October 16, 2009
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"Gliomatosis cerebri is a rare primary cerebral tumour entity characterized by diffuse infiltrative growth patterns representing a WHO grade III malignancy. The prognosis is dismal and therapeutical options are still controversial," scientists in Mannheim, Germany report (see also Angiogenesis).
"In contrast to other high-grade gliomas, angiogenesis is thought to be absent in gliomatosis cerebri. Despite this assumption, histopathological analyses of samples of six patients with gliomatosis cerebri were performed and surprisingly there was angiogenic activity, with expression of vascular endothelial growth factor and cyclooxygenase 2. It was therefore decided to ...