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Article: New findings from Wuhan University in the area of ulcerative colitis published.
- Article from:
- Gene Therapy Weekly
- Article date:
- October 15, 2009
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"The major histocompatibility complex (MHC) class I-related molecules A (MICA) is a stress-inducible cell surface antigen that is recognized by intestinal epithelial V delta 1 gamma delta T cells, natural killer (NK) cells and CD8(+) T cells with NKG2D receptor participating in the immunological reaction in the intestinal mucosa. The present study aimed to investigate the functions of the MICA*A5.1 allele in the development of ulcerative colitis (UC) in the Chinese population," scientists writing in the journal Immunology report (see also Ulcerative Colitis).
"The microsatellite polymorphisms of MICA were genotyped in 124 unrelated Chinese patients with UC and ...