|
|
Article: Scientists at Johns Hopkins University release new data on biological chemistry.
- Article from:
- Chemicals & Chemistry
- Article date:
- October 16, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
"Eukaryotic Cu,Zn-superoxide dismutases (SOD1s) are generally thought to acquire the essential copper cofactor and intramolecular disulfide bond through the action of the CCS copper chaperone. However, several metazoan SOD1s have been shown to acquire activity in vivo in the absence of CCS, and the Cu, Zn-SOD from Caenorhabditis elegans has evolved complete independence from CCS," scientists writing in the Journal of Biological Chemistry report.
"To investigate SOD1 activation in the absence of CCS, we compared and contrasted the CCS-independent activation of C. elegans and human SOD1 to the strict CCS-dependent activation of Saccharomyces cerevisiae SOD1. Using ...
Related newspaper, magazine, and journal articles:
|
|
Article: Study findings from Johns Hopkins University, ...
Science Letter;
December 30, 2008 ;
700+ words
... ... colleagues, Johns Hopkins University, Department of Biological Chemistry. The researchers ... Dept. of Biological Chemistry, Dept ... The Johns Hopkins University School of ... Sciences, Biological Chemistry. This article ...
|
|